Semisynthetic erythromycin antibiotics

Details Semisynthetic erythromycin antibiotics Semisynthetic erythromycin antibiotics

1986-06-20

1988-04-26

Brown, J. R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 72, 536 74, A61K 3170, C07H 1708

Patent

active

047405023

ABSTRACT:
Semisynthetic antibiotics with improved therapeutic properties made from erythromycin are disclosed. Certain 4"-carbamates of erythromycin, its derivatives, and their salts and esters show superior in vitro antimicrobial activity and reduced gastrointestinal stimulation compared to the parent compounds.

REFERENCES:
patent: 4283527 (1981-08-01), Sciavolino
patent: 4331803 (1982-05-01), Watanabe et al.
patent: 4349545 (1982-09-01), Gouin d'Ambrieres et al.
patent: 4496717 (1985-01-01), Adachi et al.

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