Selective thyroid hormone analogs

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

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560 52, 560 57, 560 61, 560 9, 562426, 562460, 562464, 514543, 514570, C07C 5956

Patent

active

058832947

ABSTRACT:
Selective thyroid hormone agonists are disclosed that are highly selective for the TR.beta. subtype with high binding affinity. Methods of using such agonists and pharmaceutical compositions containing them are also disclosed, as are novel procedures for their preparation.

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