Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1986-03-07
1987-12-22
Shippen, Michael L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
514729, 562506, 568700, C07C 6135, A61K 3119
Patent
active
047147148
ABSTRACT:
Analogs of arachidonic acid are provided having the structure ##STR1## wherein R is CH.sub.2 OH or CO.sub.2 H and m is 1 or 2. These compounds are useful as inhibitors of leukotriene and prostaglandin biosynthesis and as such are useful an antiallergy and antiinflammatory agents.
REFERENCES:
patent: 4442099 (1984-04-01), Nicolaou
Corey, Tetrahedron Letters, 24, pp. 265-268 (1983).
E. R. Squibb & Sons Inc.
Levinson Lawrence S.
Rodney Burton
Shippen Michael L.
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