Process for purification of phospholipids

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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2604124, C11C 100

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047145714

ABSTRACT:
A process for the separation and purification of individual phospholipids, especially phosphatidylcholine or lecithin and phosphatidylethanolamine, from mixtures containing members of the sub-class of phosphatides, incorporating methods of solvent extraction appropriate to the scale of the sample and utilizing an acetonitrile, acetonitrile-hydrocarbon, or acetonitrile-fluorocarbon solvent, which exhibit differential solubility properties towards the individual phospholipids.

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Jungalwala et al., "Biochem. J.", 155, 55-60 (1976).
Bott et al., Some Extractions and Separations with Carbon Dioxide with Carbon Dioxide at Near-Critical Conditions, in International Solvent Extraction Conference, Denver, Colorado, Aug. 26-Sept. 2, 1983, pp. 556-557.
Brunner et al., Selection of Solvents for Supercritical Extraction in International Solvent Extraction Conference, Denver, Co.; Aug. 26-Sept. 2, 1983, pp. 558-559.
Mangold, 1983, JAOCC 60 (2): 226-228.

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