Surgery – Means for introducing or removing material from body for... – Material introduced into and removed from body through...
Patent
1986-06-06
1987-12-22
Rosenbaum, C. Fred
Surgery
Means for introducing or removing material from body for...
Material introduced into and removed from body through...
604 43, 604 53, 604264, A61B 106
Patent
active
047144602
ABSTRACT:
Catheter feedback methods and systems are disclosed for optimizing the infusion of a drug, such as a chemotherapeutic agent via retrograde perfusion through the venous side of the vascular network to a selectively determined portion of a solid tumor. Monitoring and regulatory capability are provided for controlling the outflow of the drug and thereby for controlling the dose rate, the duration of exposure of the drug, the leakage factor, and the level of systemic toxicity, all critical factors in the successful treatment of solid tumors. A feedback loop for practicing the method comprises two concentric balloon catheters capable of extensive maneuvering and selective placement within the venous drainage of the vascular system, creating a third in-vivo space for repeated perfusion of the selected portion of a diseased organ as often as desired, providing maximum exposure of the chemotherapy to the tumor with minimum exposure to any other portions of the patient's body.
REFERENCES:
patent: 3435824 (1969-04-01), Gamponia
patent: 4040413 (1977-08-01), Ohshiro
patent: 4192302 (1980-03-01), Boddie
patent: 4290428 (1981-09-01), Durand, et al.
patent: 4448188 (1984-05-01), Loeb
patent: 4459977 (1984-07-01), Pizon et al.
Ausman, et al., "Isolated Perfusion of the Liver with HN.sub.2 ", Surgical Forum, 1959, vol. X, pp. 77-79.
Ausman, "Development of a Technique for Isolated Perfusion of the Liver", NY State Med. J., 1961, pp. 3993-3997.
Chung, et al., "A Technique of Isolated Perfusion of the Liver", Surgery 1962, vol. 51, No. 4, pp. 508-511.
Rosenbaum C. Fred
Vinyard Sherri E.
LandOfFree
Methods and systems for retrograde perfusion in the body for cur does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods and systems for retrograde perfusion in the body for cur, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods and systems for retrograde perfusion in the body for cur will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-817085