Streptococcus pneumoniae polynucleotides which encode folyl-poly

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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4353201, 435325, 435362, 435365, 435367, 4352523, 43525233, 536237, 935 66, 935 71, 935 72, 935 22, 935 12, C07N 2104, C12N 1531, C12N 1563

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058828982

ABSTRACT:
The invention provides folC polypeptides and DNA (RNA) encoding folC polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing folC polypeptides to screen for antibacterial compounds.

REFERENCES:
Lacks et al. J. Bact. 177(1):66-74, Jan. 1995.
Lopez, et al.., GenBank Submission, Accession No. U16156, M17362, M58706, "Sulfonamide resistance in Streptococcus pneumoniae: DNA sequence of the gene encoding dihydropteroate synthase and characterization of the enzyme." Oct. 20, 1994.

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