Method for the synthesis of nucleotide or oligonucleotide phosph

Details Method for the synthesis of nucleotide or oligonucleotide phosph Method for the synthesis of nucleotide or oligonucleotide phosph

1996-12-27

1999-09-21

Kight, John

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 231, 558 70, C07H 2102, C07H 2104

Patent

active

059556005

ABSTRACT:
This invention presents novel methods for recovery of phosphoramidites from the waste products of oligonucleotide synthesis. The methods include reacting a tribromophenoxydichlorophosphorane with a H-phosphonate in the presence of an amine.

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