Process for the production of substituted aminophthalides

Details Process for the production of substituted aminophthalides Process for the production of substituted aminophthalides

1981-12-09

1983-08-16

Fan, Jane T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549309, 562441, C07D30788

Patent

active

043992919

ABSTRACT:
Process comprises the combination of the two steps of condensing Y-benzaldehyde with N--R.sup.2 --N--R.sup.3 -aniline and 3--N--R--N--R.sup.1 -benzoic acid, under acidic conditions to produce 2-[(Y-phenyl) (4--N--R.sup.2 --N--R.sup.3 -aminophenyl)methyl]-5--N--R--N--R.sup.1 -aminobenzoic acid, and oxidizing said benzoic acid to produce 3-(Y-phenyl)-3-(4--N--R.sup.2 --N--R.sup.3 -aminophenyl)-6--N--R--N--R.sup.1 -aminophthalide.

REFERENCES:
patent: Re23024 (1948-08-01), Adams
patent: 2417897 (1947-03-01), Adams
patent: 3642514 (1972-02-01), Orita et al.
patent: 3845077 (1974-10-01), Hughes et al.
patent: 3971821 (1976-07-01), Baumann
patent: 3995088 (1976-11-01), Garner et al.
patent: 4045458 (1977-08-01), Kondo et al.
patent: 4052415 (1977-10-01), Mayer
Beilsteins Handbuch der Organische Chemie, vol. 14, p. 549.

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