Dry mix formulation for bisphosphonic acids

Details Dry mix formulation for bisphosphonic acids Dry mix formulation for bisphosphonic acids

1997-10-08

1999-03-16

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

424464, 424465, 424494, A61K 900

Patent

active

058826564

ABSTRACT:
Pharmaceutical compositions of bisphosphonic acids, and salts thereof, are prepared by direct compression/dry mix tablet formulation. These pharmaceutical compositions are useful in the treatment of disturbances involving calcium or phosphate metabolism, in particular, the treatment and prevention of diseases involving bone resorption, especially osteoporosis, Paget's disease, malignant hypercalcemia, and metastatic bone disease.

REFERENCES:
patent: 4942157 (1990-07-01), Gall et al.
patent: 5041428 (1991-08-01), Isomura et al.
patent: 5047246 (1991-09-01), Gallian et al.
patent: 5070108 (1991-12-01), Margolis
patent: 5158944 (1992-10-01), Makino et al.
patent: 5358941 (1994-10-01), Bechard et al.
patent: 5681590 (1997-10-01), Bechard et al.

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