Chiral amino-methyl ferrocene derivatives

Details Chiral amino-methyl ferrocene derivatives Chiral amino-methyl ferrocene derivatives

1991-10-07

1993-05-18

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546 2, 540541, 548402, 556144, C07F 1712

Patent

active

052123111

ABSTRACT:
A ferrocene derivatives represented by the following formula (I): ##STR1## can be a useful ligand to metals with Lewis acidity and is used as a catalyst for asymmetric synthesis with good enantioselectivity. This ferrocene derivatives is synthesized from a novel haloferrocene derivative represented by formula (II) and the haloferrocene derivative is synthesized from a novel ferrocene derivative represented by formula (III).

REFERENCES:
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The Chem. Soc. of Japan, vol. 53, No. 4, "Asymmetric Synthesis Catalyzed by Chiral Ferrocenylphosphine-Transition Metal Complexes". I. Preparation of Chiral Ferrocenylphosphines, Tamio Hayashi et al., pp. 1138-1151 (1980).
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