Alkanolamine derivatives

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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260465D, 260553A, 560 9, 560 22, 560 34, 562426, 562434, 562439, 424309, 424319, 424322, A61K 3117, A61K 31215, A61K 31275, C07C12719

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active

041713745

ABSTRACT:
Novel 1-aryloxy-3-amidoalkylamino-2-propanol derivatives, processes for their manufacture, pharmaceutical compositions containing them and methods of using them in the treatment of heart diseases. The compounds possess .beta.-adrenergic blocking activity and some of them additionally possess cardiac stimulant activity. Representative of the compounds disclosed is 1-(2-fluorophenoxy)-3-.beta.-(3-benzylureido) ethylamino-2-propanol.

REFERENCES:
patent: 3663607 (1972-05-01), Barrett et al.
patent: 3712927 (1973-01-01), Howe et al.
patent: 3732277 (1973-05-01), Koppe et al.
patent: 3928412 (1975-12-01), Smith

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