Indole and benzimidazole-substituted dihydropyrimidine derivativ

Details Indole and benzimidazole-substituted dihydropyrimidine derivativ Indole and benzimidazole-substituted dihydropyrimidine derivativ

1991-12-16

1993-05-18

Tsang, Cecilia

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514 81, 514 86, 514215, 514258, 514260, 514269, 514272, 514274, 514275, 540521, 544231, 544232, 544243, 544244, 544278, 544279, 544280, 544284, 544286, 544292, 544295, 544310, 544316, 544318, 544319, 544321, 544322, A61K 31505, A61K 31675, C07D21126, C07D21156, C07D40306, C07D48702

Patent

active

052121771

ABSTRACT:
Novel compounds having the formula ##STR1## and its isomer ##STR2## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7 and X are as defined herein. These compounds inhibit the action of angiotensin II and are useful, therefore, for example, an antihypertensive agents.

REFERENCES:
patent: 4340598 (1982-07-01), Furukawa et al.
patent: 4355040 (1982-10-01), Furukawa et al.
patent: 4582847 (1986-04-01), Furukawa et al.
patent: 4812462 (1989-03-01), Blankley et al.
patent: 4816463 (1989-03-01), Blankley et al.
patent: 4820843 (1989-04-01), Aldrich et al.
patent: 4855301 (1989-08-01), Atwal et al.
patent: 4870186 (1989-09-01), Aldrich et al.
patent: 4874867 (1989-10-01), Aldrich et al.
patent: 4880804 (1989-11-01), Carini et al.
Karnail S. Atwal et al., "Substituted 1,4-Dihydropyrimidines, 3.Synthesis of Selectively Functionalized 2-Hetero-1,4-dihydropyrimidines", J. Org. Chem, 1989, 54, pp. 5898-5907.

Affiliated with

Also associated with

Rating

Indole and benzimidazole-substituted dihydropyrimidine derivativ does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Indole and benzimidazole-substituted dihydropyrimidine derivativ, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Indole and benzimidazole-substituted dihydropyrimidine derivativ will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-804644