Method of using N-acetyl-2,3-Didehydroleucine acylase for the pr

Details Method of using N-acetyl-2,3-Didehydroleucine acylase for the pr Method of using N-acetyl-2,3-Didehydroleucine acylase for the pr

1992-04-20

1993-05-18

Naff, David M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Enzymatic production of a protein or polypeptide

435228, 435106, C12P 2100, C12P 1304, C12N 980

Patent

active

052120694

ABSTRACT:
A novel N-Acetyl-2,3-didehydroaminoacid-acylase is obtained by cultivating Zoogloea ramigera DSM 4306. The new enzyme can be used in a coupled enzyme system with an L-Leucinedehydrogenase for the enzymatic conversion of N-Acetyl-2,3-didehydroleucine to L-Leucine, D- or L-tryptophylglycine to D- or L-tryptophaneamide and glycine, as well as other tryptophanedipeptides to tryptophaneamides and free amino acids.

REFERENCES:
patent: 5134073 (1992-07-01), Kula et al.
Nishida et al., Enzyme Microb Technol., vol. 9, pp. 479-483, 1987.
Hummel et al., Appl. Microbiol. Biotechnol., vol. 27, pp. 283-291, 1987.

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