Spiro-quinolylhydantoins

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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Details

546 18, 546174, 546 89, C07D49120, A61K 3147, C07D51320

Patent

active

041761855

ABSTRACT:
Novel spiro-quinolylhydantoin derivatives useful as aldose reductase inhibitors and as therapeutic agents for the treatment of chronic diabetic complications are disclosed. Preferred compounds include spiro[imidazolidin-4,4'-pyrano[3,2-h]quinolin]-2,5-dione and spiro[imidazolidin-4,4'-pyrano[2,3-f]quinolin]-2,5-dione.

REFERENCES:
patent: 3876659 (1975-04-01), Houlihan et al.
patent: 4117230 (1978-09-01), Sarges

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