Sulfamoyl derivatives of 8-.beta.-aminomethylergoline

Details Sulfamoyl derivatives of 8-.beta.-aminomethylergoline Sulfamoyl derivatives of 8-.beta.-aminomethylergoline

1977-11-03

1979-11-27

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424250, 424261, 544125, 544361, 546 67, 2602444, C07D45702, A61K 3148

Patent

active

041761820

ABSTRACT:
Novel sulfamoyl derivatives of 8.beta.-aminomethyl ergoline having the general formula: ##STR1## are disclosed, which have interesting pharmacological properties and are useful as anti-migrainic, anti-hypertensive and psychopharmaceutically active drugs. In the method for their preparation a compound having the formula: ##STR2## is reacted, in an aprotic solvent and at a temperature of between -20.degree. C. and +150.degree. C., with a compound having the formula: ##STR3##

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