Contraceptive methods and formulations for use therein

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

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424423, 424424, 424430, 424432, 424433, 424484, 424485, 424486, 424487, 424488, 424489, 424DIG14, 424449, 514 2, 514 12, 514 21, 514800, 514841, 514842, 514843, 530850, 530853, 128830, 128832, 128833, A61F 202, A61F 606, A61K 3738, A61K 950, A61K 914, C07K 1506, C07K 1702, C07K 1714

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active

052119521

ABSTRACT:
Contraceptive devices which are effective for extended periods of time are described, in the form of means for releasing an effective amount of a gonadotropin hormone releasing hormone composition and means for releasing an effective amount of an estrogenic hormone over a first period of time, and means for releasing an effective amount of a progestogen for a second period of time, the second period of time being substantially shorter than and running simultaneously with a portion of the first period of time. The gonadotropin hormone releasing hormone composition is selected from gonadotropin hormone releasing hormone, gonadotropin hormone releasing hormone analogues, gonadotropin hormone releasing hormone agonists, gonadotropin hormone releasing hormone antagonists and mixtures thereof. Contraceptive methods employing the devices are also described.

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