Processes for the production of antibiotic 1-oxadethiacephalospo

Organic compounds -- part of the class 532-570 series – Organic compounds – Chalcogen in the nitrogen containing substituent

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260141, C07D49804

Patent

active

044725760

ABSTRACT:
Disclosed is a process for preparing antibiotic 1-oxadethiacephalosporins via diazo-species I: ##STR1## wherein: A is acyl; R.sup.1 is H or OCH.sub.3 ; and R.sup.2 is a protecting group.

REFERENCES:
patent: 4138486 (1979-02-01), Narisada et al.
patent: 4174316 (1979-11-01), Christensen et al.
patent: 4226866 (1980-10-01), Christensen et al.
Malcolm M. Campbell and Graham Johnson, "Formation of Enantiomeric 4-Oxa-2,6-diazabicyclo (3.2.0) hept-2-en-7-ones+from Methyl 6 and 6-Phenoxyacetamidopenicillanates", J.C.S. Perkin I, 1975, pp. 1932-1934.

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