Antimicrobial 8-alkoxy-6,7-dihydro-5-methyl-9-fluoro-1-oxo-1H,5H

Details Antimicrobial 8-alkoxy-6,7-dihydro-5-methyl-9-fluoro-1-oxo-1H,5H Antimicrobial 8-alkoxy-6,7-dihydro-5-methyl-9-fluoro-1-oxo-1H,5H

1983-03-17

1984-09-18

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546 94, 546165, 546167, 546180, A61K 3147, C07D45504

Patent

active

044724071

ABSTRACT:
The 8-alkoxy-6,7-dihydro-5-methyl-9-fluoro-1-oxo- 1H,5H-benzo[ij]quinolizine-2-carboxylic acids are disclosed as potent antimicrobial agents with a broad spectrum of activity. Esters, acyl chlorides, amides, alkylaminoalkyl ester salts and pharmaceutically acceptable carboxylate salts are also disclosed. Methods of using these compounds, pharmaceutical compositions comprising these compounds and synthetic intermediates for preparing these compounds are also described.

REFERENCES:
patent: 3896131 (1975-07-01), Gerster
patent: 4380543 (1983-04-01), Stern
patent: 4399134 (1983-08-01), Ishikawa et al.

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