Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1996-08-01
1999-09-21
Patterson, Jr., Charles L.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4352543, 4353201, 530350, 530400, 536 234, 536 235, C12N 1562, C12N 1564, C12N 1580, C07K 1479
Patent
active
059553162
ABSTRACT:
The subject invention provides for the production of lactoferrins and lactoferrin polypeptide fragments using the host cells Aspergillus in combination with novel plasmid constructs. More specifically, the subject invention provides novel vector constructs capable of producing lactoferrins and lactoferrin polypeptide fragments in Aspergillus host cells. More particularly, the subject invention provides for novel plasmid constructs suitable for use with Aspergillus and especially Aspergillus awamori, niger and oryzae host cells, which enables them to produce large amounts of recombinant lactoferrins and lactoferrin polypeptide fragments.
REFERENCES:
patent: 5304633 (1994-04-01), Tomita et al.
patent: 5571691 (1996-11-01), Conneely et al.
patent: 5571697 (1996-11-01), Conneely et al.
patent: 5571896 (1996-11-01), Conneely et al.
LeGrand, D., et al., Biochimica et Biophysica Acta, vol. 787, "Characterization and localization of an iron-binding 18-kDa glycopeptide isolated from the N-terminal half of human lactotransferrin", pp. 75-84, 1984.
Valenti, P., et al., FEMS Microbiology Letters, vol. 33, "Interaction between lactoferrin and ovotransferrin and Candida cells", pp. 271-275, 1986.
Anderson, B. F., et al., Proceedings of the National Academy of Sciences, U.S.A., vol. 84, "Structure of human lactoferrin at 3.2A resolution", pp. 1769-1773, 1987.
Epstein, J. B., et al., Reviews of Infectious Diseases, vol. 6, "Oral Candidiasis: Pathogenesis and host defense", pp. 96-106, 1984.
Anderson, B. F., et al., Journal of Molecular Biology, vol. 209, "Structure of human lactoferrin: Crystallographic structure analysis and refinement at 1.8A resolution", pp. 711-734, 1989.
Soukka, T., et al., FEMS Microbiology Letters, vol. 90, "Fungicidal effect of human lactoferrin against Candida albicans", pp. 223-228, 1992.
Conneely Orla M.
Headon Denis R.
O'Malley Bert W.
Agennix Inc.
Halluin Albert P.
Moore William W.
Patterson Jr. Charles L.
LandOfFree
Expression of processed recombinant lactoferrin and lactoferrin does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Expression of processed recombinant lactoferrin and lactoferrin , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Expression of processed recombinant lactoferrin and lactoferrin will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-79357