Intermediates and processes for preparing 4-substituted 2-5(H)-f

Details Intermediates and processes for preparing 4-substituted 2-5(H)-f Intermediates and processes for preparing 4-substituted 2-5(H)-f

Filed on

1992-10-28

Date issued

1994-03-29

Examiner

Ivy, C. Warren

Patent Class

Organic compounds -- part of the class 532-570 series

SubClass

Organic compounds

SubSubClass

Heterocyclic carbon compounds containing a hetero ring...

Other Related Categories

549222, 549313, 549318, 549483, 549486, 549497, 549499, C07D30742, C07D30748

Type

Patent

Status

active

Patent number

052986330

Description

ABSTRACT:
Anti-inflammatory 4-substituted 2-furanones are made from intermediates having the formulas: ##STR1##

REFERENCES:
patent: 5112853 (1992-05-01), Garst
patent: 5134128 (1992-07-01), Lee et al.
patent: 5169963 (1992-12-01), Lee
patent: 5171863 (1992-12-01), Lee et al.
patent: 5171864 (1992-12-01), Lee
Elliott, et al. (I), "Chemical Abstracts", vol. 69, 1968, Col. 106542t.
Glombik, et al., "Chem. Ber", vol. 116, 1983, pp. 1366-1374.
Lee, "Tetrahedron Letters", No. 25, 1979, pp. 2297-2300.
Elliott, et al. (II), "J. Chem. Soc." Per. Trans I, vol. 6 1981, pp. 1782-1789.
Klein, "J. Amer. Chem. Soc.", vol. 107, 1985, pp. 2573-2574.
Trahanovsky, et al., "J. Amer. Chem. Soc.", vol. 103, 1981, pp. 6691-6695.
Graziano, et al, "Photosensitized Oxidation Of Furans, Part 12, Solvent Effects In Thermal Rearrangement Of The 2,5-Peroxides Of 2,5-Unsubstituted Furans", J. Chem, Soc., Perkin Trans, 1, (8), 1833-9, Apr. 19, 1989.
David Nettleton, et al, Inflammation Research Association, Fifth International Conference Poster Session, Phospholipase A.sub.2 Inhibition By Dihydrofuranones, Sep. 23-27, 1990.

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