Thiazolidone compounds and method of using the same as a vasodil

Details Thiazolidone compounds and method of using the same as a vasodil Thiazolidone compounds and method of using the same as a vasodil

1992-03-24

1994-03-29

Gerstl, Robert

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514342, 546280, 548188, C07D 7714, A61K 31425

Patent

active

052985164

ABSTRACT:
Compounds of formula (I): ##STR1## wherein W represents a sulfur atom and X represents a group of formula --N(R.sup.1)--, or W represents a group of formula --N(R.sup.1)-- and X represents a sulfur atom; R.sup.1 is hydrogen, alkyl or aralkyl; R.sup.2 and R.sup.3 are each hydrogen, alkyl, aralkyl, aryl or aromatic heterocyclic; R.sup.4 is hydrogen, alkyl or aralkyl; and A is alkylene which is optionally substituted by carboxy; and pharmaceutically acceptable salts and esters thereof, have a valuable vasodilatory activity.

REFERENCES:
patent: 4200640 (1980-04-01), Nagano et al.
patent: 4923886 (1990-05-01), Shiokawa

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