Diamino acid derivatives as antihypertensives

Details Diamino acid derivatives as antihypertensives Diamino acid derivatives as antihypertensives

1992-08-04

1994-03-29

Cashion, Jr., Merrell C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 18, 530331, 530332, A61K 3117

Patent

active

052984923

ABSTRACT:
Novel diamino acid derivative dual inhibitors of neutral endopeptidase and angiotensin converting enzyme of the formula ##STR1## wherein: Z is amino, lower alkylamino, di-(lower alkyl)amino R.sup.9 C(O)NH-- or an optionally substituted guanidino group;

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