Disposable comb for electrophoresis device

Chemistry: electrical and wave energy – Apparatus – Coating – forming or etching by sputtering

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2041528, G01N 2726

Patent

active

049099183

ABSTRACT:
A disposable comb for a vertical gel cassette of a vertical electrophoresis device is disclosed. The comb is formed from a single thin sheet of a plastic, preferrably biaxial polystyrene, which has at least a slight degree of resilience. A comb is rectangular in shape, and has a plurality of equally spaced parallel ridges or ribs which extend from one side of the sheet to the other (from top to bottom as the comb is inserted into a vertical gel cassette). The comb has a plurality of relatively wide coplanar flat portions alternating with relatively narrow parallel ridges, which resemble the teeth of a comb. The tops of the ridges are slightly convex. The disposable comb is placed into a vertical gel cassette comprising a pair of closely spaced walls, so that the coplanar flat portions of a comb engaged inside surface of one wall while the ridges engage in the inside of the surface of relatively wide spaced paralled sample wells which are adpated to receive a mixture of macromolecules which are to be separated, alternating with realtively narrow spacer channels.

REFERENCES:
patent: 3616387 (1971-10-01), Siebert et al.
patent: 4035377 (1977-07-01), Detroy
patent: 4325796 (1982-04-01), Hoefer et al.
patent: 4431506 (1984-02-01), Gorman, Jr. et al.
patent: 4762743 (1988-08-01), von Alven et al.

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