Oligonucleotides complementary to mycobacterial nucleic acids

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435 6, C07H 2102, C07H 2104

Patent

active

055213006

ABSTRACT:
Disclosed are nucleic acid oligonucleotides which are substantially complementary to nucleic acids from Mycobacteria, and subgeneric classes thereof. More specifically, the oligonucleotides are complementary to ribosomal RNA (rRNA) and the DNA encoding rRNA (rDNA). Uses for such oligonucleotides include detection of Mycobacteria by hybridization and amplification of Mycobacterial nucleic acid by polymerase chain reaction.

REFERENCES:
patent: 4358535 (1982-11-01), Falkow et al.
patent: 4410660 (1983-10-01), Straus
patent: 4489158 (1984-12-01), Straus
patent: 4575484 (1986-03-01), Straus
Regensburger, A., et al. Complete nucleotide sequence of a 235 ribosomal RNA gene from Micrococcas luteus Nucl. Acids Res. (19889) 16:2344.
GenBank Locus MLRN235 from Regensburger et al. compared with GenBank Locus ML55235 from Liesacker et al. reference of record.
B. Boddinghaus et al. J. Clin. Microbiol. 28, 1751-1759 (1990).
D. A. Stahl and J. W. Urbance J. Bacteriol. 172, 116-124 (1990).
J. Neefs et al. Nucl. Acids Res. 18 (suppl.), 2237-2317 (1990).
W. Liesack et al. FEBS Lett. 281, 114-118 (1991).
Wallace and Miyada Methods in Enzymology 152, 432-442 (1987).
Zainuddin and Dale, Journal of General Microbiology 135:2347-2355 (1989).
Conville et al., Diagn. Microbiol. Infect. Dis. 12: 217-219 (1989).
Butcher et al., Gut 29:1222-1228 (1988).
Ellner et al., Journal of Clinical Microbiology 26:1349-1352 (1988).
Colombrita et al., J. Med. Microbiol. 32:271-273 (1990).
Stockman and Roberts, Abst. Annu. Meet. Am. Soc. Microbiol. 88:137 (1988).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Oligonucleotides complementary to mycobacterial nucleic acids does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Oligonucleotides complementary to mycobacterial nucleic acids, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Oligonucleotides complementary to mycobacterial nucleic acids will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-788062

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.