Method for making succinic acid, anaerobiospirillum succinicipro

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound

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4352521, 435822, C12P 746, C12P 104

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active

055210759

ABSTRACT:
A method for making succinic acid employs a fluoroacetate resistant variant of Anaerobiospirillum succiniciproducens. The fluoroacetate variant produces a succinic acid product which contains less acetic acid than the product obtained using the parent strain under identical conditions. A preferred variant FA-10 is obtained from A. succiniciproducens (ATCC No. 29305). A method of obtaining the variant also is described.

REFERENCES:
patent: 5143833 (1992-09-01), Datta
patent: 5143834 (1992-09-01), Glassner et al.
patent: 5168055 (1992-12-01), Datta et al.
Podkovyrov SM et al, J. Gen. Microbiol. 139(2):223-228 (1993).
Samuelov NS et al, App Environ Microbiol 57(10):3013-3019 (1991).
Rothstein, D. M., (1986). Clostridium thermosaccharolyticum strain deficient in acetate production. J. Bacteriol. 165:319-320.

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