Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1991-03-20
1992-08-04
Shippen, Michael L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514520, 514544, 514546, 514571, 514618, 514621, 514679, 548253, 558405, 560 9, 560 11, 560 53, 560138, 562426, 562429, 562463, 564162, 564169, A61K 3141
Patent
active
051359405
ABSTRACT:
Compounds of the Formulae: ##STR1## are antagonists of leukotrienes of C.sub.4, D.sub.4 and E.sub.4, the slow reacting substance of anaphylaxis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents.
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Derwent Abstract 23065 K/10 (corresponds to French 2,509,725).
Young, et al., J. Med. Chem., 29, 1573-1576 (1986).
Belanger Patrice C.
Fortin Rejean
Guindon Yvan
Rokach Joshua
Yoakim Christiane
DiPrima Joseph F.
Lopez Gabriel
Merck Frosst Canada Inc.
Shippen Michael L.
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