Method for decreasing reaginic antibody levels

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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536 25, A61K 3170

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active

051359189

ABSTRACT:
A method for achieving long term relief from the symptoms of atopic allergy, comprising parenteral administration of Vitamin B.sub.12 to selected patients, is produced. Vitamin B.sub.12 acts to reduce the levels of reaginic antibody (immunoglobulin) in these patients, and this effect persists beyond the period of treatment. The regimen may include oral administration of Vitamin B.sub.12 as well as other vitamins.

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patent: 4806354 (1989-02-01), Green
The Pharmacological Basis of Therapeutics, 7th Ed., Goodman et al eds., MacMillan Publishing Co., New York, 1985, pp. 1325-1332.
Dewdney, "Prospects for modulation of the specific immune response in allergic diseases," Ch. 6 in Allergy and Asthma, A. B. Kay ed., Blackwell Scientific Publications, London, GB, 1989, pp. 91-98.
Katz, "Suppression of the IgE response with human proteins developed by biotechnology," Ch. 8 in Allergy and Asthma, A. B. Kay ed., Blackwell Scientific Publications, London, GB, 1989, pp. 113-125.
Hamberger, R. N. (1975) Science 189: 389.
Caruselli, M. (1952) RIF.MED. 66; 849-851 (informal English translation also attached).
Trampiz, G. (1959) Folia Clinica International, Jul.-Aug. 264-266 (informal English translation also attached).

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