Substituted 7,12-methano dibenzazocines and 8,13-methano dibenza

Details Substituted 7,12-methano dibenzazocines and 8,13-methano dibenza Substituted 7,12-methano dibenzazocines and 8,13-methano dibenza

1974-03-25

1976-08-24

Coughlan, Jr., Paul M.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260239D, 2605705R, 2605705C, 424244, C07D22314, C07D22316

Patent

active

039766349

ABSTRACT:
Substituted 7,12-methano-dibenzazocines and 8,13-methanodibenzazonines, e.g., 7,12-dihydro-6,13-dimethyl-7,12-methano-6H-dibenz [c,f] azocine, are prepared by cyclizing 3-benzylamino or 3-phenethylamino -2-alkyl-indan-1-ols and are useful as anti-inflammatory agents.

REFERENCES:
patent: 3496165 (1970-02-01), Houlihan et al.
patent: 3498988 (1970-03-01), Houlihan et al.
patent: 3642777 (1972-02-01), Houlihan et al.
patent: 3781270 (1973-12-01), Houlihan et al.
G. A. Olah "Friedel-Crafts and Related Reactions", vol. II, part 1, p. 519, Interscience, (1964).

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