Endothelin receptor antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

549362, 549436, 549416, 549444, 549447, A61K 3136, C07D31754

Patent

active

058176934

ABSTRACT:
Novel indane and indene derivatives are described which are endothelin receptor antagonists.

REFERENCES:
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Komendantov et al., C.A., 88:190,677p (1978).
Ihara et al., Biochem & Biophys Res. Comm., 178(1), 132-137 (1991).
Miyata et al., Journal of Antibiotics, 45(7), 1041-1046 (1992).
Koelsch, J. Org. Chem, 25, 2088 (1960).

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