Mosaic microcolumns, slabs, and separation media for electrophor

Details Mosaic microcolumns, slabs, and separation media for electrophor Mosaic microcolumns, slabs, and separation media for electrophor

1990-10-15

1992-08-04

Niebling, John

Chemistry: electrical and wave energy

Processes and products

Electrostatic field or electrical discharge

2041801, 204299R, 428327, C25B 100, B01D 5702, B01D 6142

Patent

active

051356279

ABSTRACT:
A method and compositions for separating molecules based on molecular size, shape, affinity, chirality, weight, charge, and hydrogen bonding, using a mosaic matrix formed by polymerizing a dispersion of dispersoids within a polymeric matrix. The dispersoids and matrix can be of the same or different hydrophobicity or hydrophilicity. The dispersoids can be porous or non-porous. The mosaic matrix can be used with existing chromatographic and electrophoresis apparatus to effect an enhanced separation of molecules, particularly of nucleic acids and peptides, by application of a solution and/or an electrical field to the matrix. The solution can form a pH, ionic, or composition gradient, and be applied using gravity or under pressure. The electrical field can be continuous, pulsed, or two-dimensional.

REFERENCES:
patent: 3922432 (1975-11-01), Renn
patent: 4856706 (1989-09-01), Karger et al.
patent: 4865707 (1989-09-01), Karger et al.
patent: 4883597 (1989-11-01), Perlman
patent: 4911807 (1990-03-01), Burd
patent: 4963243 (1990-10-01), Ogawa
Brown and Pietrzyk, J. Chromatography 466, 291-300 (1989).
Issaq, et al., J. Liquid Chromatography 11(2), 333-348 (1988).

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