Thienopyridine derivatives and their pharmaceutical use

Details Thienopyridine derivatives and their pharmaceutical use Thienopyridine derivatives and their pharmaceutical use

1991-08-13

1992-09-01

Dentz, Bernard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514301, 546 80, 546114, A61K 31435, C07D49504

Patent

active

051439190

ABSTRACT:
Thienopyridine derivatives of the formula (I): ##STR1## wherein the ring A is an optionally substituted benzene ring; the ring B is an optionally substituted thiophene ring: X is a group of the formula: ##STR2## (wherein R.sup.1 is hydrogen, alkyl or alkoxy; and n is 0 or 1) or a group of the formula: ##STR3## (wherein R.sup.2 is hydrogen or alkyl); Y is a single bond, --NH--, alkylene having 1 or 2 carbon atoms or --CH.dbd.CH--; and R.sup.3 is an optionally substituted hydrocarbon group, or their salts are disclosed. They show strong ACAT inhibitory activities.

REFERENCES:
patent: 3862152 (1975-01-01), Kuwada et al.

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