Pharmaceutical preparations

Details Pharmaceutical preparations Pharmaceutical preparations

1990-05-24

1992-09-01

Shen, Cecilia

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514269, 514274, 544298, 544309, 544313, 544315, 544317, A61K 31505, C07D23926, C07D23930, C07D23934

Patent

active

051439174

ABSTRACT:
The synthesis and application of N(1)-n-alkyl-pyrimidinium-salts are described. These surfactants have a very small critical micelle concentration ()CMC) in the order of 10.sup.-5 -10.sup.-7 Mol/Liter. These N(1)-n-alkyl-pyrimidinium components have pharmacological activities and can act as antimetabolites.

REFERENCES:
W. Forth, Allgemeine und Spezielle Pharmkologie und Toxikologie, 4th edition, 1983, p. 616.
F. J. Fendler et al., J. Chem. Soc. Perkin III, 1097 (1977).
Attwood et al., J. Phys. Chem. 74, 3529 (1970).

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