Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1990-05-03
1992-09-01
Schain, Howard E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 8, 514 12, 530350, 530409, 424405, 435 697, C07K 308, A61K 3700, A61K 3907, A61K 3912
Patent
active
051439050
ABSTRACT:
The invention relates to a method for increasing the host range or toxicity of an insecticidal protein exerting its activity via interaction with the gut epithelium of insects within its host range, by delivering the insecticidal protein to the gut epithelium of a target insect with the aid of an other, targeting protein capable of binding to the gut epithelium of the target insect. The targeting protein may, for example, be of viral origin or, alternatively, may be a bacterial protein or protein domain having high affinity for the lipid components of membranes.
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Federici Brian A.
Sivasubramanian Natarajan
Koh Choon
Schain Howard E.
The Regents of the University of California
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