Short total synthesis or morphinan compounds which uses cyclizat

Details Short total synthesis or morphinan compounds which uses cyclizat Short total synthesis or morphinan compounds which uses cyclizat

1983-12-22

1986-09-23

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546 15, 546 45, 546 74, 546146, 546149, C07D48902

Patent

active

046136681

ABSTRACT:
There is disclosed herewith a method of producing morphinan compounds by total synthesis which incorporates utilization of N-cycloalkylcarbonyl compounds, which show certain advantages over the prior art which has been previously expressed in U.S. Pat. No. 4,368,326.

REFERENCES:
patent: 3299072 (1967-01-01), Bartels-Keith
patent: 3322771 (1967-05-01), Bartels-Keith
patent: 4003903 (1977-01-01), Schwartz
patent: 4058531 (1977-11-01), Monkovic et al.
patent: 4115389 (1978-09-01), Monkovic
patent: 4139534 (1979-02-01), Lim et al.
Bartels-Keith, J. Chem. Soc. (C), 1966, pp. 617-624, (1966).
Monkovic, et al., J. Am. Chem. Soc., vol. 100, No. 14, pp. 4609-4610, (Jul. 5, 1978).
Rice, J. Org. Chem., vol. 45, No. 15, pp. 3135-3137, (Jul. 18, 1980).
Weller et al., J. Med. Chem, vol. 19, No. 10, pp. 1171-1175, (10/76).
Wiberg and Kass, J. Am. Chem. Soc., 107:988-95, 1985, refs. 1-30.
Wiberg et al., J. Am. Chem. Soc., 107:1003-07, 1985.
Houben-Weyle, vol. 4, Part 3, p. 651, "Methods of Organic Chemistry," Springer-Verlag Press, 1971.
E. H. Rodd, Chemistry of Carbon Compounds, vol. II-A, p. 27.
Giacomini, et al., J. Org. Chem., 45:519-22, 1980.
Olah, et al., Synthesis, 1973, pp. 661-664.
Olah, et al., Science, vol. 206, pp. 13-20, 1979.
Howells and McCown, Chemical Reviews, 1977, pp. 69-92.
Schultz, J. Org. Chem., 36(3):383-386, 1971.
M. C. Brande, et al., (Eds), Advances in Biochemical Pharmacology, vol. 8, 1974, p. 46.

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