Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase
Patent
1978-01-03
1979-08-28
Wiseman, Thomas G.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Oxidoreductase
435822, 435853, 435856, 435857, 435885, C12D 1310
Patent
active
041660056
ABSTRACT:
An improved process for producing .alpha.-glycerophosphate oxidase provides yields of more than 1500 U per liter. The enzyme is produced by growing a member of the family Lactobacillaceae in a medium comprising pyruvate and an inducer for .alpha.-glycerophosphate oxidase. In the preferred embodiment, a medium comprising a mixture of glucose and pyruvate as carbon sources provides a synergistic effect on the production of .alpha.-glycerophosphate oxidase.
REFERENCES:
koditschek et al., ".alpha.-Glycerophosphate Oxidase in Streptococcus faecium F24", J. Bact., vol. 98, No. 3, pp. 1063-1068 (1969).
Jacobs et al., "The Purification and Properties of the .alpha.-Glycerophosphate Oxidizing Enzyme of Streptococcus faecalis 10Cl", Arch. Biochem. Biophys., vol. 88, pp. 250-255 (1960).
Jacobs et al., "Comparison of the Mechanism of Glycerol Oxidation in Aerobically and Anaerobically Grown Streptococcus faecalis", J. Bact., vol. 79, pp. 532-538 (1960).
Gunsalus et al., "The Oxidation of Glycerol by Streptococcus faecalis", J. Bact., vol. 49, pp. 347-357 (1945).
Gunsalus, "Products of Anaerobic Glycerol Fermentation of Streptococcus faecalis", J. Bact., vol. 54, pp. 239-244 (1947).
Claridge et al., "Oxidation of Glycerol by Streptococcus faecalis", J. Bact., vol. 84, pp. 1181-1186 (1962).
Kamihara et al., "Pyruvate Oxidation and Related Metabolism in Streptococcus faecalis, II, The Physiological Role of Pyruvate Oxidation", Chem. Abst., vol. 69, No. 13, p. 4664, Abs. No. 49970e (1968).
Kamihara et al., "Pyruvate Oxidation and Related Metabolism in Streptococcus faecalis, III, Effects of Cultural Conditions on Growth in a Lipid Deficient Medium", Chem. Abst., vol. 71, No. 21, p. 94, Abs. No. 99136y (1969).
"American Type Culture Collection Catalogue of Strains", 12th Ed., Rockville, Md., (1976), p. 118.
Goodhue Charles T.
Masurekar Prakash S.
Eastman Kodak Company
Hilst Ronald P.
Wiseman Thomas G.
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