Rat CNP complementary DNA and precursor protein

Details Rat CNP complementary DNA and precursor protein Rat CNP complementary DNA and precursor protein

1991-09-11

1999-10-26

Carlson, Karen Cochrane

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

530350, C07H 1700, C07K 1400

Patent

active

059731346

ABSTRACT:
A cDNA coding for a rat derived CNP (rCNP: C-type natriuretic pepteide), and a rat derived CNP precursor protein and derivatives thereof are disclosed.
The rat derived CNP precursor is represented by the following amino acid sequence.

REFERENCES:
Kojima et al. 1990 FEBS 276:209-213.
Minamino et al. 1990 Biochem Biophys. Res. Commun. 170:973.
Minamino et al; N-Terminally Extended Form of C-Type Nartriuretic Peptide (CNP-53) Identified in Porcine Brain; Biochemical and Biophysical Research Communications; vol. 170, No. 2, Jul. 31, 1990, pp. 973-979.
Kojima et al, Cloning and sequence analysis of cDNA encoding a precursor for a rat brain nattriuretic peptide; Biochemical and Biophysical Research Communications; vol. 159, No. 3, Mar. 31, 1989, pp. 1420-1426.
Kojima et al, Cloning and sequence analysis of a cDNA encoding a precursor for rat C-type natriuretic peptide (CNP), Febs Letters, vol. 276, No. 1/2, Dec. 1990, pp. 209-213.
Kita et al. 1989. Life Science 44:1541-1545.
Steinhelper et al 1990 Hypertension 16(3):301-307, Abstract.
Seilhamer et al. 1989 Biochem Biophys Res. Commun 165:650-658.
Lazure et al 1988 FEBS Lett. 238:300-306.
Vlasuk et al. 1986 Biochem Biophys Res Commun 136:396-403.

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