Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1997-04-30
1999-10-26
Huff, Sheela
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
435 6, 435 691, 435 693, 4353201, 435273, 4352523, 536 235, 530350, C07H 2100, C07H 2102
Patent
active
059731303
ABSTRACT:
The present invention provides a human Ras-like protein (RLP) and polynucleotides which identify and encode RLP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. In addition, the invention provides methods for producing RLP and for treating or preventing disorders associated with expression of RLP.
REFERENCES:
Drivas, G.T., et al., "Characterization of Four Novel ras-Like Genes Expressed in a Human Teratocarcinoma Cell Line," Molecular and Cellular Biology, 10(4):1793-1798 (1990) (GI 190877).
Lee, C., et al., "Rin, a Neuron-Specific and Calmodulin-Binding Small G-Protein, and Rit Define a Novel Subfamily of Ras Proteins," The Journal of Neuroscience, 16(21) 6784-6794 (1996) (GI 1656005).
Drivas, G.T., et al., (GI 190877) GenBank Sequence Database (Accession M31468) National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland 2084 (1990).
Drivas, G.T., et al. (GI 190876) GenBank Sequence Database (Accession M31468) National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland 2084 (1990).
Lee, C., et al., (GI 1656005) Sequence Database (Accession U71205) National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland 2084 (1997).
Lee,C., et al., (GI 1656004) Sequence Database (Accession U71205) National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland 2084 (1997).
Ren, M., et al., "It its active form, the GTP-binding protein rab8 interacts with a stress-activated protein kinase," Proc. Natl. Acad. Sci. USA, 93:5151-5155 (1996).
Corley Neil C.
Goli Surya K.
Hillman Jennifer L.
Billings Lucy J.
Huff Sheela
Incyte Pharmaceuticals Inc.
Mohan-Peterson Sheela
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