Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1998-03-24
1999-10-26
Owens, Amelia
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
504291, 549271, A61K 31335, C07D31300
Patent
active
059729945
ABSTRACT:
Biotransformation products of a fermentation with Streptomyces sp., (Merck Culture Collection MA7165) ATCC No. 55946 are potent antifungal agents. These products may be useful in the treatment of diseases caused by fungal pathogens such as Candida sp. and Cryptococcus neoformans.
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Annals of the NY Academy of Sciences, vol. 544, pp. 128-140 (1988), by H. Achenbach, et al.
J. of Antibiotics, vol. XXXIX, No. 12, pp. 1760-1764 (1986).
J. of Antibiotics, vol. XXXVIII, No. 12, pp. 18061809 (1985).
J. of Antibiotics, vol. XXXVIII, No. 12, pp. 1810-1812 (1985).
J. of Antibiotics, vol. XXXIX, No. 7, pp. 1016-1020 (1986).
Tetrahedron Letters, vol. 26, No. 50, pp. 6167-6170 (1985).
Harris Guy H.
Mandala Suzanne Miller
Rosenbach Mark J.
Shafiee Ali
Sigmund Janet M.
Daniel Mark R.
Korsen Elliott
Merck & Co. , Inc.
Owens Amelia
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