Mercury binding polypeptides and nucleotides coding therefore

Details Mercury binding polypeptides and nucleotides coding therefore Mercury binding polypeptides and nucleotides coding therefore

1997-07-03

1999-10-26

Eisenschenk, Frank C.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 71, 435 792, 43524027, 514 12, 514 13, 514 14, 514 15, 514 16, 514 17, 514 18, 4241411, 5303881, 5303871, 5303889, 5303899, G01N 3353, C12P 2104, C07K 1600, C07K 1644

Patent

active

059726563

ABSTRACT:
Metal binding polypeptides which include an amino acid sequence coding for a variable region of a monoclonal antibody which immunoreacts with a mercury cation and nucleotides which include a nucleic acid sequence coding for the variable region are provided. The invention is also directed to fusion proteins which include a phage coat protein or portion thereof and the monoclonal antibody heavy chain variable region. The invention also provides bacteriophages which include the fusion protein in their coat. In addition, methods for detecting, removing, adding, or neutralizing mercuric cations in biological or inanimate systems through the use of the mercury binding polypeptides are provided.

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