Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-12-08
1995-07-04
Prescott, Arthur C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514214, A61K 3140
Patent
active
054300495
ABSTRACT:
This invention describes a method for the treatment of a patient afflicted with a hyperproliferative disorder which comprises administering to a patient a effective amount of a compound which is an analogue of nicotinic acid and inhibits nicotinic acid metabolism in vitro in human platelets. Additionally, a method for determining the effectiveness of various compounds in treating a hyperproliferative disorder is described.
REFERENCES:
patent: 4725596 (1988-02-01), Friary et al.
patent: 5182289 (1993-01-01), Ting et al.
patent: 5264578 (1993-11-01), Chandraratna
"Inhibition of Nicotinic Acid Metabolism in Human Blood Platelets by Nicotinic Acid Analogs and Nonsteroidal Antiinflammatory Drugs" Gaut, 1994.
"Asprin in the Prevention of Colorectal Cancer" Editorials, Aug. 1994, vol. 121, No. 4, pp. 303-304.
Annals of Internal Medicine, Aug. 1994, vol. 121, No. 4, "Asprin Use and the Risk for Colorectal Cancer and . . . " pp. 241-246.
Possible Publiction in the Annuals: "Asprin Use and Adenoma in Male Health Professionals", Zane N. Gaut, M.D., Ph.D., 1994.
Drug Therapy, Saven and Piro, vol. 330, No. 10, Mar. 10, 1994, pp. 691-698 (1993).
Cancer Research, vol. 53, pp. 1322-1327; Mar. 15, 1993; "Aspirin Use and Risk of Fatal Cancer"; Michael J. Thun, et al.
The New England Journal of Medicine, 1991, vol. 325, No. 23, Dec. 5, 1991, pp. 1593-1596; "Aspirin Use and Reduced Risk of Fatal Colon Cancer"; Michael J. Thun, et al.
Cancer Research, vol. 53, Dec. 15, 1993; "Correspondence re M. J. Thun et al. Aspirin Use and Risk of Fatal Cancer . . . "; Zane N. Gaut; p. 6074.
LandOfFree
Treating hyperproliferative disorders does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Treating hyperproliferative disorders, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Treating hyperproliferative disorders will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-760394