2-(4-pyrrlidinyl)-1H-pyrido[4,3-b]indol-1-ones and related compo

Details 2-(4-pyrrlidinyl)-1H-pyrido[4,3-b]indol-1-ones and related compo 2-(4-pyrrlidinyl)-1H-pyrido[4,3-b]indol-1-ones and related compo

1993-11-08

1995-07-04

Chang, Celia

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514212, 540597, 540599, 540602, 546 86, A61K 3144, C07D 4706

Patent

active

054300380

ABSTRACT:
Novel 2-(4-piperidinyl)-1H-pyrido[4,3-b]indol-1-ones and related compounds, intermediates and processes for the preparation thereof, and methods of treating psychoses employing compounds and compositions thereof are disclosed.

REFERENCES:
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patent: 4148895 (1979-04-01), Lattrell
patent: 4432978 (1984-02-01), Welch
patent: 4977159 (1990-12-01), Sevrin
patent: 5013733 (1991-05-01), Coates
patent: 5183820 (1993-02-01), Coates
Berger "Medicinal Chemistry" pp. 871-872 John Wiley and Sons, (1982).
Merk Index, Merk Publications, pp. 599, 1208 9th Edition, 1976.
G. A. Bahadur, et al., Journal Chemical Society, Perkin I, 1688 (1980), published in Great Britain and entitled "Reactions of 4,5-Dihydro-5-methylpyrano[4,3-b]indole-1,3-dione: a Synthesis of N-Methylisotryptophol".
"Comprehensive Organic Chemistry--The Synthesis and Reactions of Organic Compounds" D. Barton and W. D. Ollis, Editors, vol. 2, Pergamon Press, New York, N.Y., 1979, pp. 34 to 38 and 994 to 999.
"Burger's Medicinal Chemistry", 4th Edition, Part I., The Basis of Medicinal Chemistry, M. E. Wolf, Editor, John Wiley and Sons, New York, N.Y., pp. 55 to 105 (1982).

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