Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1982-09-30
1985-03-19
Hollrah, Glennon H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
544360, 544379, 544380, 544381, 544391, 260239BC, 2602444, 514218, 514255, A61K 31495, C07D24104, C07D40104
Patent
active
045059136
ABSTRACT:
Substituted anthranilamides of the formula ##STR1## in which R.sub.1 is hydrogen or an aliphatic, cycloaliphatic or cycloaliphatic-aliphatic hydrocarbon radical, R.sub.2 is hydrogen, lower alkyl, lower alkoxy, halogen or trifluoromethyl, R.sub.3 is hydrogen or an aliphatic or substituted or unsubstituted araliphatic or heteroaryl-aliphatic hydrocarbon radical and alk and alk' are identical or different lower alkylene radicals which separate the nitrogen atoms by 2 or 3 carbon atoms, and salts thereof, possess analgesic, anti-inflammatory and anti-allergic properties and may be used as active ingredients of analgesic, anti-inflammatory and anti-allergic pharmaceuticals. They are prepared, for example, by reacting an acid of the formula ##STR2## or a reactive functional derivative thereof, with an amine of the formula ##STR3## or a reactive derivative or salt thereof.
REFERENCES:
patent: 3926961 (1975-12-01), Ferrini et al.
patent: 4182769 (1980-01-01), Cherkofsky et al.
Ferrini Pier G.
Haas Georges
Rossi Alberto
Ciba-Geigy Corporation
Feit Irving N.
Hollrah Glennon H.
Turnipseed James H.
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