Cysteine derivatives

Details Cysteine derivatives Cysteine derivatives

1973-06-07

1976-04-13

Rotman, Alan L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602948G, 260470, 260481R, 260516, 2601125R, 424263, 424309, 424314, 424319, C07C 6952

Patent

active

039503879

ABSTRACT:
S-substituted cysteines, alkyl esters of S-substituted cysteines and S-substituted glutathiones in which the substituent on the S atom is allyl, geranyl, cinnamyl, benzylidene-3-butyl, 1-(para-chlorophenyl)ethyl and (pyridyl-3)methyl but excluding S-allyl cysteine bring about a reduction in atheromatic deposits in the aorta of test animals as well as a reduction in hypercholesterolemia and are of low toxicity. They may be used by the conventional routes for the treatment of human atheromatic conditions and disorders of the lipid metabolism.

REFERENCES:
patent: 3531490 (1970-09-01), Friedman et al.
Frankel et al., J. Chem. Soc., London, pp. -1390-1393, part 1, (1960).

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