Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1982-01-15
1983-07-19
Rosen, Sam
Drug, bio-affecting and body treating compositions
Lymphokine
424178, 424199, 424358, 424365, A61K 4502, A61K 3726, A61K 4700
Patent
active
043943721
ABSTRACT:
A process for producing lipid membrane structures (vesicles or liposomes) is disclosed, wherein a solution of bilayer forming compounds in a narrowly-defined two component solvent system is dispersed in an aqueous solution and, subsequently, at least a portion of that solvent system is stripped off. This process permits the readily-reproducible production of lipid membrane structures under gentle processing conditions, ideal for use when they contain pharmaceutically-active materials.
REFERENCES:
patent: 3932657 (1976-01-01), Rahman
patent: 4183918 (1980-01-01), Asher et al.
patent: 4224179 (1980-09-01), Schneider
patent: 4235871 (1980-11-01), Papahadjopoulos et al.
patent: 4308166 (1981-12-01), Marchetti et al.
patent: 4310505 (1982-01-01), Baldeschwieler et al.
patent: 4310506 (1982-01-01), Baldeschwieler et al.
Deamer, et al., Biochemica et Biophysica Acta, 443, 629-634 (1976).
Kremer, et al., Biochemistry, 16, 3932-3935 (1977).
Szoka, et al., Proc. Natl. Acad. Sci. USA, 75, 4194-4198 (1978).
Davies and Rideal, Interfacial Phenomenon, Academic Press: New York, 343-449 (1961).
Groves, Chemistry and Industry, 17, 417-423 (1978).
Becher, Emulsions: Theory and Practice, 2d, Reinhold: New York, 293-297 (1965).
Gregoriadis, The New England Journal of Medicine, 295, 704-710, 765-770 (1976).
Szoka, et al., Annual Review of Biophysical Engineering, 9, 467-508 (1980).
Huang, Biochemistry, 8, 344-352 (1969).
Rhoden, et al., Biochemistry, 18 4173-4176 (1979).
Batzri, et al., Biochemica et Biophysica Acta, 298, 1015-1019 (1973).
Goldstein Steven J.
Rosen Sam
Schaeffer Jack D.
Suter David L.
The Procter & Gamble & Company
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