Cyclic N-substituted derivatives of 1,4-benzene disulphonamide

Details Cyclic N-substituted derivatives of 1,4-benzene disulphonamide Cyclic N-substituted derivatives of 1,4-benzene disulphonamide

1974-10-04

1976-01-13

Moyer, Donald B.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424244, 424246, 424275, A61K 31535, A61K 3133, A61K 3154, A61K 3138

Patent

active

039326403

ABSTRACT:
Compounds of the formulae: ##SPC1##
And the salts thereof with pharmaceutically acceptable cations wherein n and m are each two or three; X is oxygen or sulphur; R.sup.2 and R.sup.3, when taken separately, are each hydrogen or alkyl having 1 to 4 carbon atoms; R.sup.2 and R.sup.3, when taken together, are alkylene having 2 to 4 carbon atoms; Y is methylene or a single bond; R.sup.4 and R.sup.5, when taken separately, are each hydrogen, hydroxy or alkoxy having 1 to 5 carbon atoms, and R.sup.4 and R.sup.5, when taken together, are oxo or alkylene dioxy having 2 to 4 carbon atoms, each oxygen atom in R.sup.4 and R.sup.5, when taken separately, and in R.sup.4 and R.sup.5, when taken together, being separated from the nitrogen atom of the heterocyclic ring by two or more carbon atoms, said compounds being cerebral vasodilators.

REFERENCES:
patent: 3165550 (1965-01-01), Holland et al.

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