Process for the preparation of substituted guanidines

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

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564230, 564237, 564240, C07C12912

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043586139

ABSTRACT:
Guanidines are one of the strongest organic bases and find applications where this property is needed, such as in phase transfer catalysis in the form of their substituted derivatives. Their use, however, has been hampered by their expensive nature due to the only mediocre yields in their preparation. The present invention provides a process for the preparation of substituted guanidines in high yields.

REFERENCES:
Bredereck, Hellmut et al., Chem. Ber., vol. 94, pp. 2278-2295, (1961).
Eilingsfeld, Heinz et al., Chem. Ber., vol. 97, pp. 1232-1245, (1964).
Gavin, David F. et al., J. Org. Chem., vol. 32, pp. 2511-2516, (1967).
Smith, P. A. S., Open-chain Nitrogen Compounds, vol. 1, pp. 281-282, (1965).

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