Creative kinase-MB immunoassay for myocardial infarction and rea

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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435 76, 435 792, 435 17, 4351722, 43524027, 436524, 436528, 436811, 436815, 436536, 5303871, 5303881, 53038826, 5303893, G01N 33573, G01N 3353, C07K 1528

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active

053825152

ABSTRACT:
Methods and reagents for determining the lapse of time since an acute disease event, such as the occurrence of a myocardial infarction, are presented. A serum or plasma sample is assayed to determine the concentration of two different analytes selected from a group of creatine kinase-MB species. From these measurements, the time of the acute event can be more accurately determined. Novel antibodies, labeled and insolubilized derivatives of these antibodies, labeled proteins, and kits containing one or more of these reagents are also described.

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