Chemical apparatus and process disinfecting – deodorizing – preser – Process disinfecting – preserving – deodorizing – or sterilizing – Using disinfecting or sterilizing substance
Patent
1993-07-16
1995-01-17
Snay, Jeffrey R.
Chemical apparatus and process disinfecting, deodorizing, preser
Process disinfecting, preserving, deodorizing, or sterilizing
Using disinfecting or sterilizing substance
422103, 53425, 53426, 53471, B65B 5510
Patent
active
053824067
ABSTRACT:
The present invention is directed to a method for the on-line sterile filling of a container with a sterile solution from a filling nozzle in a filling head. A container having an open end and a hollow body portion for receiving the sterile solution is provided. The container also includes an access passageway tube having first and second ends and a pierceable septum sealing the passageway at an intermediate position within the tube. The first open end of the access passageway tube is sealed in the open end of the container so as to close the hollow body portion of the container, which is then sterilized. Later, before on line filling, the second end of the access passageway tube is isolated from the surrounding environment by axially advancing and sealably seating the filling head at the second end of the access passageway tube. The isolated end of the access passageway tube is then sterilized for a time period sufficient to reduce the viable micro-organism population present to a predetermined level. Then a filling nozzle is advanced from the filling head through the isolated and sterilized end of the passageway tube and pierces the septum of the tube. After the sterilized hollow body portion is filled with the sterile solution, the access passageway is sealed between the hollow body portion and the filling nozzle.
REFERENCES:
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patent: 3514919 (1970-06-01), Ashton et al.
patent: 3531908 (1970-10-01), Rausing et al.
patent: 4494363 (1985-01-01), Rica et al.
patent: 4805378 (1989-02-01), Anderson
Block, S. S. "Disinfection, Sterilization and Preservation", 3d ed. Lea & Febiger, 1983. pp. 3-4, 47 and 89-92.
Kruger Robert J.
Mayoral Joaquin
Abbott Laboratories
Snay Jeffrey R.
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