Monitoring of drug levels

Surgery – Truss – Pad

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A61B 514

Patent

active

046588337

ABSTRACT:
The present invention provides a method of determining the concentration of a selected drug in the body of a subject comprising the steps of holding a liquid collecting means comprising an absorbent substantially inert member 1 in a position in close proximity to an eye 4 of the patient for collecting the fluid 7 therefrom; allowing the tear fluid collected to come into contact with reagent means 3 for reacting with said selected drug so as to produce, after a predetermined time interval, a physically detectable change dependent, at least semi-quantitatively, upon the concentration of said drug; and determining the physical change in said reactive portion after a predetermined interval of time.

REFERENCES:
patent: 3036894 (1962-05-01), Forestiere
patent: 3266868 (1966-08-01), Harvill
patent: 3509872 (1970-05-01), Truhan
patent: 3769961 (1973-11-01), Fatt et al.
patent: 4164559 (1979-08-01), Miyata et al.
patent: 4184491 (1980-01-01), McGannon
patent: 4190060 (1980-02-01), Greenleaf et al.
patent: 4329999 (1982-05-01), Phillips
patent: 4426451 (1984-01-01), Columbus

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