Process for improving vigor and mood in normal human patients

Details Process for improving vigor and mood in normal human patients Process for improving vigor and mood in normal human patients

1981-08-31

1984-03-06

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

A61K 31195

Patent

active

044354240

ABSTRACT:
The level of a catecholamine in neuronal synapses is increased in order to improve vigor by administering a neutral amino acid composition to a human wherein an increased brain level of a catecholamine is effected when the composition contains increased amounts of tyrosine and/or phenylalanine. Increased or decreased brain levels of serotonin are obtained when the amino acid composition contains increased or decreased amounts of tryptophan.
The neutral amino acid composition can be administered alone or concomitantly with a drug which increases or decreases catecholaminergic neurotransmission.

REFERENCES:
Wurtman et al., Science, 185-pp. 183-184, 7-12-74.
Gibson et al., Biochem. Pharmacology, 26, pp. 1137-1142, 6/77.
Chem. Abst., 79-87422S (1973).
Page, Scientific American, Dec. 1957, pp. 52-56.

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